The most common types of bone tumour are osteosarcoma and
Ewing's sarcoma, both of which are most frequently diagnosed in children and young adults.
Other less common types of bone cancer include: Chondrosarcoma (a cancer arising in
cartilage cells, usually found in adults between ages 50-75, though the less common
mesenchymal-chondrosarcoma is more frequent in younger patients), Malignant Fibrous
Histiocytoma of bone (MFH), Chondoma (a rare low grade malignancy occuring mostly between
ages 30 -70), and other rare tumours.
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Bone Cancer FAQ
Answers to some of the frequently asked questions about bone cancer. It is produced by an
international panel of bone cancer specialists. It includes separate Ewing's Sarcoma FAQ
and Osteosarcoma FAQ.
BoneTumor.org (H. DeGroot MD,
University of Massachusetts) an educational web site about bone tumors with sections for
patients and health professionals. Includes treatment summaries and an online atlas of
bone tumours with radiology and pathology images.
Musculoskeletal Tumor Society A
non-profit organization bringing together orthopaedic surgeons and other physicians to
forward musculoskeletal oncology research. MSTS was founded in the early 1980's and has
members accross North and South America
Pediatric
Oncology Resource Center: Bone Tumors (USA) This page contains information and links
on various aspects of bone cancer. It is part of the Pediatric Oncology Resource Center, a
site produced by parents of children with cancer, hosted by Association of Cancer Online
Resources.
Stories and
Faces: Bone Cancer (Pediatric Oncology Resource Center) List of home pages of children
affected by bone cancer
Local
Control of Pediatric Sarcomas of Bone (Bone Cancer Research Fund, Indiana University)
Short paper by Bruce T. Rougraff, M.D., Assistant Professor of Orthopaedic Surgery and
Pathology
Malignant Bone Tumors
(USA) Part of a SEER report on cancer incidence and survival among children and
adolescents; 1975-1995. PDF format.
Online Atlas of Bone
Tumours (bonetumor.org, University of Massachusetts) includes pages on both benign and
malignant bone tumours with radiology images and pathology slides.
Pagets Disease
(Radiology Museum, Central Middlesex Hospital, UK) text and radiology images. Pagets
disease is a benign condition, but does have the potential for malignant transformation
Ewing's sarcoma / Peripheral Primitive
Neuroectodermal Tumours (PNET) of bone is a type of cancer usually found in children and
young adults. The peak incidence is between ages 10 and 20, it is less common in children
under 5 or in adults over 30. Ewing's s can occur in any bone in the body; the most common
sites are the pelvis, thigh, lower leg, upper arm, and rib. The tumour is composed of
small round blue cells. Ewing's sarcoma can also arise in soft tissue (extra-skeletal);
see Soft Tissue Sarcoma in this guide.
Patient's
information for Ewing's Sarcoma (CancerNet) Information about the disease, staging,
and treatment overviews. It is reviewed each month by a panel of medical experts.
Childrens
Hospital Los Angeles - Ewing's sarcoma / pPNET genetics study A confidential study
investigating the role of genes in Ewing's sarcoma looking for participation by patients
and their parents and siblings from around the world. DNA is extracted from mouthwash or
blood samples from volunteers.
E-SARCOMA-UK
An Email list open to anyone interested in Ewing's sarcoma. It is primarily aimed at UK
based families and health professionals, both others are very welcome. The list was set up
by parents who lost their son to Ewing's sarcoma.
European
Intergroup Ewing's Sarcoma Study Historical details of the EICESS '92 trial, now
closed to entry. EICESS is a collaboration of groups and treatment centres in Germany, UK,
Netherlands, and elsewhere.
Ewing's
Sarcoma (American Cancer Society) an online booklet including details about diagnosis,
staging, treatment etc.
Ewing's
Sarcoma (UK) a factsheet produced by the United Kingdom Children's Cancer Study Group
and CancerBacup linked to the UKCCSG booklet "A Parent's Guide to Children's
Cancers".
Ewing's
Sarcoma FAQ (Bone Cancer FAQ) Answers to some of the frequently asked questions about
Ewing's Sarcoma / PNET. It is produced by an international panel of bone cancer
specialists.
Maddy's
Story (in Band-aides and Blackboards) the story of Maddy who was diagnosed with
Ewing's sarcoma of the femur with lung metastases at age 13.
Paula's
story Paula was diagnosed with Ewing's sarcoma of the spine in 1981, treated at the
M.D. Anderson Cancer Center, USA.
Robert and
Karen's Home and Links Page Thiese pages include information about Robert amd Karen's
son Matthew, who was diagnosed with Ewing's sarcoma in 1996. There are pictures of Matthew
along with his poems, plus derails of treatments recieved and links to related sites.
Physician's
PDQ statement for Ewing's Sarcoma (CancerNet) A referenced overview of the disease,
cellular classification, staging, and current treatment overviews. It is reviewed each
month by experts at the NCI.
Ewing's
sarcoma (Radiology Museum, Central Middlesex Hospital, UK) text and radiology images
Physician's statement for
Ewing's Sarcoma (START, European School of Oncology) Referenced statement including
sections on epidemiology, pathology, diagnosis, staging, treatment and follow-up produced
by an editorial board of top European oncologists.
Osteogenic Sarcoma (osteosarcoma) is a bone forming
cancer. It is the most frequent type of bone tumour and is most common between the ages of
15 to 25. Over 90% of tumours are located in the metaphysis (the growing ends of the
bone), the most common sites are the bones around the knee which account for 80% of cases.
Osteosarcomas vary greatly in radiological and pathological features and therefore needs
careful diagnosis to differentiate this from other bone tumours. Most are high grade
intramedullary osteosarcomas, about 5% are low grade lesions, some are secondary
osteosarcomas (for example those caused by radiation therapy).
Patient's
information for Osteosarcoma (CancerNet) Information about the disease, staging, and
treatment overviews. It is reviewed each month by a panel of medical experts.
Madison Research Group (USA) a
private corporation devoted to the study of osteosarcoma, particularly molecular biology.
The web site includes information about treatment, incidence, molecular biology and
glossary.
Osteosarcoma
(UK) a factsheet produced by the United Kingdom Children's Cancer Study Group and
CancerBacup linked to the UKCCSG booklet "A Parent's Guide to Children's
Cancers".
Osteosarcoma
Cancer Information (American Cancer Society) an online booklet including details about
diagnosis, staging, treatment etc.
Osteosarcoma
FAQ (Bone Cancer FAQ) Answers to some of the frequently asked questions about
Osteosarcoma. It is produced by an international panel of bone cancer specialists.
Physician's
PDQ statement for Osteosarcoma (CancerNet) A referenced overview of the disease,
cellular classification, staging, and current treatment overviews. It is reviewed each
month by experts at the NCI.
Diagnosis:
Osteosarcoma MRI Teaching Files - an 11 year-old boy with a one month history of right
knee pain. Case Author(s): Thomas H. Vreeland , 4/7/94
Osteosarcoma
This Web site includes medical images and referenced text by W. Enneking MD and R. Rathe
MD, University of Florida.
Osteosarcoma
(Radiology Museum, Central Middlesex Hospital, UK) text and radiology images
Osteosarcoma
(bonetumor.org) a summary with radiology images and pathology slides.
Physician's statement for
Osteosarcoma (START, European School of Oncology) Referenced statement including
sections on epidemiology, pathology, diagnosis, staging, treatment and follow-up produced
by an editorial board of top European oncologists. [Go to Chapters]
Small cell
osteosarcoma (bonetumor.org) a summary with radiology images and pathology slides.
Chondrosarcoma is a type of cancer arising in
cartilage cells, usually found in adults between ages 40-75, though the less common
mesenchymal-chondrosarcoma is more frequent in younger patients. Chondrosarcoma accounts
for 20% of all primary malignant bone tumours. The most common sites of disease are the
pelvis, ribs and upper thigh, the tumour is rarely found below the knees or below the
elbows. In extremely rare cases the disease can arise in soft tissue (Extraosseous
Chondrosarcoma).
Soft tissue sarcomas are malignant tumours that may
arise in any of the mesodermal tissues (muscles, tendons, vessels that carry blood or
lymph, joints, and fat). Sarcomas are a diverse range of tumours, they are named after the
type of soft tissue cell they arise from. Types of soft tissue sarcomas include; alveolar
soft-part sarcoma, angiosarcoma, fibrosarcoma, leiomyosarcoma, liposarcoma, malignant
fibrous histiocytoma, hemangiopericytoma, mesenchymoma, schwannoma, peripheral
neuroectodermal tumours, rhabdomyosarcoma, synovial sarcoma, and other types. In terms of
treatment these different sub-types are usually treated in the same way using a uniform
soft tissue protocol.
SARCOMA-MED
(ACOR) a list for medical queries relating to sarcomas - not a general discussion list.
Specialist sarcoma physicians have volunteered to answer medical queries posted to the
list.
Sarcoma.Net An educational site
for sarcoma patients including sarcoma facts, information about clinical trials and links.
The site is by George Demetri, MD a sarcoma specialist at the Dana-Farber Cancer
Institute.
CancerLit:
Sarcoma (National Cancer Institute) On-line abstracts for health professionals. Sorted
by month and year for soft tissue sarcoma / rhabdomyosarcoma
Connective Tissue
Oncology Society An international group of physicians and scientists founded in 1995
to advance the care of patients and to advance basic and clinical research into connective
tissue tumors. The site includes details of the society, membership, meetings, registry
etc
International
Musculoskeletal Tumor Registry (Connective Tissue Oncology Society) data is being
collected for ongoing CTOS studies. As well as data on common tumor types the registry
aims to collect data on rare tumors.
Sarcoma
(Journal) a peer reviewed international journal publishing papers covering all aspects of
connective tissue oncology research. Table of Contents Email service.
Childhood soft tissue sarcomas account for
approximately 10% of all childhood cancers. About half of all childhood soft tissue
sarcomas are rhabdomyosarcoma, which arises from skeletal muscle, these are most common
between the ages of 2 and 6. The other soft tissue sarcomas of childhood include a wide
range of different histologies including fibrosarcoma, leiomyosarcoma, liposarcoma,
schwannoma, soft tissue Ewing's / peripheral neuroectodermal tumours, synovial sarcoma and
many other types. These non-rhabdo sarcomas are more common in adults, but these tumours
usually behave quite differently in children compared to the same tumours in adults.
Alistair's
Home Page Alistair was diagnosed with Rhabdomyosarcoma, age 11. This page tells his
story with information about the disease and treatment and how Alistair has done since
finishing therapy in February 1996. Great pictures and art work.
Intergroup Rhabdomyosarcoma Study Group
(USA) The IRSG is funded by the National Cancer Institute and conducts research into
rhabdomyosarcoma. The web site includes material for public and health professionals
including details about the disease and information about clinical trials.
Joshua Gilbert Rhabdomyosarcoma
Appeal (UK) a charity founded in the memory of Joshua who died from Rhabdomyosarcoma
in 1994. The appeal was established to raise money for research into this disease. The
site includes details of the charity, research reports, events etc.
Pediatric
Oncology Resource Center: Rhabdomyosarcoma (USA) This page contains information and
links on various aspects of childhood leukemia. It is part of the Pediatric Oncology
Resource Center, a site produced by parents of children with cancer, hosted by Association
of Cancer Online Resources.
Rhabdomyosarcoma
(American Cancer Society) an online booklet including details about diagnosis, staging,
treatment etc.
Rhabdomyosarcoma
(UK) a factsheet produced by the United Kingdom Children's Cancer Study Group and
CancerBacup linked to the UKCCSG booklet "A Parent's Guide to Children's
Cancers".
Soft tissue sarcomas are malignant tumours that may
arise in any of the mesodermal tissues (muscles, tendons, vessels that carry blood or
lymph, joints, and fat). The peak age incidence is around 50 years. Sarcomas are a diverse
range of tumours, they are named after the type of soft tissue cell they arise from. Types
of soft tissue sarcomas include; alveolar soft-part sarcoma, angiosarcoma, fibrosarcoma,
leiomyosarcoma, liposarcoma, malignant fibrous histiocytoma, hemangiopericytoma,
mesenchymoma, schwannoma, peripheral neuroectodermal tumours, rhabdomyosarcoma, synovial
sarcoma, and other types.
Kaposi's sarcoma is a type of cancer where malignant
cells are found in the tissues under the skin, lining of the mouth, nose, and anus.
Symptoms may include red or purple patches (lesions) on the skin and other parts of the
body. Many (though not all) Kaposi's sarcomas are AIDS related.
Physician's
PDQ statement for Adult Soft Tissue Sarcoma (CancerNet) A referenced overview of the
disease, cellular classification, staging, and current treatment overviews. It is reviewed
each month by experts at the NCI.
Physician's information
on Soft Tissue Sarcoma (START, European School of Oncology) Referenced statement
including sections on epidemiology, pathology, diagnosis, staging, treatment and follow-up
produced by an editorial board of top European oncologists. [Go to Chapters]
Patient's
information for Kaposi's Sarcoma (CancerNet) Information about the disease, staging,
and treatment overviews. It is reviewed each month by a panel of medical experts.
Kaposi's Sarcoma
(The Body: an- AIDS and HIV Information Resources)
Physician's
PDQ statement for Kaposi's Sarcoma (CancerNet) A referenced overview of the disease,
cellular classification, staging, and current treatment overviews. It is reviewed each
month by experts at the NCI.
Desmoplasic Small Round Cell
Tumour (DSRCT) (UK) pages by the partner of a young man diagnosed with DSRCT in 1987.
The site includes personal treatment updates, information about the disease, treatment
info, medical reports, histology slides, links etc.
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