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Liver Cancer

Primary liver cancer is a disease in which the cells of liver become cancerous (malignant). Primary liver cancer is different from cancer that has spread from another place in the body to the liver. The liver is found in the upper right side of the abdomen. It is an an important organ which is involved in digesting food and converting it to energy and it also filters and stores blood. Liver cancer is relatively rare, known risk factors for liver cancer are prior hepatitis B or C infections or cirrhosis of the liver. There are two main types of liver cancer in adults: hepatocellular carcinoma and cholangiocarcinoma. Hepatoblastoma is another type of liver cancer which mostly occurs in children. Some types of liver cancer produce abnormaly high levels of alpha-fetoprotein (AFP) which can aid diagnosis.

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Information for Patients and the Public

• Corticosteroids for the resolution of malignant bowel obstruction in advanced gynaecological and gastrointestinal cancer (Cochrane Collaboration) Synopsis and abstract of a systematic review.
• Hepatobiliary Cancer Overview (Memorial Sloan-Kettering Cancer Center)
• Liver Cancer Information (American Cancer Society) an online booklet including details about diagnosis, staging, treatment etc.
• LIVER-ONC - Liver Cancer Electronic Support Group Email discussion list
• Living with Liver Cancer by Paul Huckabay
• Neoadjuvant and adjuvant therapy for operable hepatocellular carcinoma (Cochrane Collaboration) Abstract of a systematic review.
• Oncolink Menu for Gastrointestinal Cancer
• Paediatric - Liver Tumours (Royal Marsden Hospital, UK) An on-line booklet.
• Patient's information for Adult Liver Cancer (CancerNet) Information about the disease, staging, and treatment overviews. It is reviewed each month by a panel of medical experts.
• Questions and Answers about Liver Cancer (CancerNet)
• Understanding Cancer of the Liver (BACUP, UK) An on-line booklet

Information for Health Professionals / Researchers

• Cancer, Hepatocellular - Genetic information (OMIM, National Center for Biotechnology Information, USA)
• CancerLit: Gastrointestinal Cancers (National Cancer Institute) On-line abstracts for health professionals. Sorted by month and year for Screening, Anal, Colorectal, Esophageal, Bile Duct, Gallbladder, Gastric ca., Carcinoid, Liver, Pancreatic, Small Intesatine
• Case study: A 2 year old girl with yolk sac ca. arising in a mature teratoma of the liver (Department of Pathology, University of Pittsburgh)
• Case study: A sixty-five year old male with primary hepatic lymphoma (Department of Pathology, University of Pittsburgh)
• Case study: Carcinoid tumor arising in a Meckel's diverticulum in a 70 year old man (Department of Pathology, University of Pittsburgh)
• Case study: Pediatric Liver Tumor (Pathology Caces for Diagnosis) a case study of a child with hepatocellular carcinoma. Pathology images, references etc.
• Corticosteroids for the resolution of malignant bowel obstruction in advanced gynaecological and gastrointestinal cancer (Cochrane Collaboration) Synopsis and abstract of a systematic review.
• Gastrointestinal Pathology (WebPath, USA) Pathology Images - including some cancer related.
• GI Cancer
• Hepatic Pathology (WebPath, USA) Pathology Images - including some cancer related.
• Hepatocellular Carcinoma -Diagnostic + Interventional Radiology University of Pisa (Department of Radiology)
• Liver Cancer Oncogene; LCO - Genetic information (OMIM, National Center for Biotechnology Information, USA)
• LIVER-ONC - Liver Cancer Electronic Support Group Email discussion list
• Meta Index of Gastroenterology Lists (Hardin Meta Directory of Internet Health Sources)
• Neoadjuvant and adjuvant therapy for operable hepatocellular carcinoma (Cochrane Collaboration) Abstract of a systematic review.
• Oncolink Menu for Gastrointestinal Cancer
• Physician's PDQ Statement - Prevention of Aerodigestive Tract Cancer (CancerNet)
• Physician's PDQ statement for Adult Liver Cancer (CancerNet) A referenced overview of the disease, cellular classification, staging, and current treatment overviews. It is reviewed each month by experts at the NCI.

Childhood Liver Cancer

Childhood liver tumours are rare. There are two main types of liver cancer; hepatoblastoma and hepatocellular carcinoma. Liver cancer can be found in children of all ages; Hepatoblastomas are more common in patients aged under 3 years, while hepatocellular carcinomas are usually found in patients aged under 4 or between the ages of 12 and 15.

• Patient's PDQ information for Childhood Liver Cancer (CancerNet) Information about the disease, staging, and treatment overviews. It is reviewed each month by a panel of medical experts.
• Childhood Liver Cancer (UK) a factsheet produced by the United Kingdom Children's Cancer Study Group and CancerBacup linked to the UKCCSG booklet "A Parent's Guide to Children's Cancers".
• Childhood Liver Disease Foundation (UK) a national registered children's charity concerned with all childhood liver disorders. (no information about childhood liver cancer)
  
• Physician's PDQ statement for Childhood Liver Cancer (CancerNet) A referenced overview of the disease, cellular classification, staging, and current treatment overviews. It is reviewed each month by experts at the NCI.
• OncoLink Childhood Liver Cancer Menu
• Childhood Hepatic Tumors (USA) Part of a SEER report on cancer incidence and survival among children and adolescents; 1975-1995. PDF format.
• Medline Search: Childhood Liver Cancer (PubMed)   Limit search to: [Last Year]  Limit search to: [Last 2 Years]   Limit search to: [Reviews]

Extra-Hepatic Bile Duct Cancer

• Patient's information for Extrahepatic Bile Duct Cancer (CancerNet) Information about the disease, staging, and treatment overviews. It is reviewed each month by a panel of medical experts.
  ********** Information for Health Professionals ***********
• Physician's PDQ statement for Extrahepatic Bile Duct Cancer (CancerNet) A referenced overview of the disease, cellular classification, staging, and current treatment overviews. It is reviewed each month by experts at the NCI.
• Medline Search: Extra-Hepatic Bile Duct Cancer (PubMed)   Limit search to: [Last Year]  Limit search to: [Last 2 Years]   Limit search to: [Reviews]