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Skin Cancer

Skin cancer is the most common type of cancer and accounts for half of all new cancers in Western populations. It occurs more often in people with light coloured skin who have had a high exposure to sunlight. The two most frequent types of skin cancer are Basal Cell Carcinomas and Squamous Cell Carcinoma (often grouped under "non-melanoma skin cancer"). The third most frequent skin cancer is Melanoma, this is a malignancy of the cells which give the skin it's colour (melanocytes). In addition there are a number of other, less common cancers starting in the skin including Merkel cell tumours, cutaneous lymphomas, and sarcomas (see the pages on sarcoma and lymphoma in this guide).

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General Resources

Malignant Melanoma

Melanoma is a malignancy of the skin in which melanocytes (the cells which give the skin it's colour) become cancerous. Melanoma occurs most frequently in white people, and is rare in people with dark skin; it is usually found in adults, though occasionally melanoma may develop in children and adolescents. Over exposure to sunlight can cause skin changes which can lead to melanoma. Half of all melanomas are thought to arise in a benign (non-cancerous) pigmented nevus (a mole). Moles are very common and normally change only slightly over time; however in melanoma there may be a more rapid increase in size - symptoms include a darker or variable discoloration, itching, and possibly ulceration and bleeding.

 

Non-Melanoma Skin Cancer

Basal Cell Carcinoma is the most common type of skin cancer, it occurs when basal cells (round cells found in the outer layer of skin) become cancerous. The second most common type of skin cancer is Squamous Cell Carcinoma, this is where squamous cells (the flat, scaly cells on the surface of the skin) become malignant . Cure rates are very high for both basal cell carcinoma and squamous cell carcinoma. In addition there are a number of other, less common cancers starting in the skin including Merkel cell tumours and cutaneous lymphomas and sarcomas (see the sections on sarcoma and lymphoma for more information about these).

 

Merkel Cell Cancer

Merkel cell cancer (also known as trabecular cancer, or neuroendocrine cancer of the skin) is a rare type of malignancy developing on or just beneath the skin. These tumours can develop at any age, but the peak incidence is between ages 60 - 80. They are more frequent in white people, the most common sites of diseases are the face or scalp and other areas of high sun exposure.

 

Dermatofibrosarcoma protuberans

Prevention of Skin Cancer 

 

Dermatology Links

 

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